42 Results for "

Pulsatilla campanella Fisch. exRegel et Tiling.

" in MedChemExpress (MCE) Product Catalog:
Products (42)

42 Results for "Pulsatilla campanella Fisch. exRegel et Tiling." in MCE Product Catalog:

35
Isoliquiritigenin
Isoliquiritigenin
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35 Publications Verification
Cat. No.: HY-N0102
CAS No.: 961-29-5
Synonyms: GU17; ISL; Isoliquiritigen; SJ000286237
Category:  

Plants Infection Flavonoids Microorganisms Chalcones Leguminosae Phenols Polyphenols Disease Research Fields Glycyrrhiza uralensis Fisch. Inflammation/Immunology

Target:  

Aldose Reductase Influenza Virus Autophagy Apoptosis

Isoliquiritigenin is an anti-tumor flavonoid from the root of Glycyrrhiza uralensis Fisch., which inhibits aldose reductase with an IC50 of 320 nM. Isoliquiritigenin is a potent inhibitor of influenza virus replication with an EC50 of 24.7 μM.
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6
Pulchinenoside C
Pulchinenoside C
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6 Cited Publications
Cat. No.: HY-N0205
CAS No.: 129741-57-7
Synonyms: Anemoside B4
Category:  

Triterpenes Terpenoids Ranunculaceae Plants Disease Research Fields Pulsatilla chinensis (Bunge) Regel Cancer

Target:  

Others

Pulchinenoside C (Anemoside B4) is Pulsatilla koreana Nakai that have many numerous biological effects in vitro, including enhancing hypoglycemic, anti-tumor, neuroprotective and anti-angiogenic activity.
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1
Pulsatilla saponin D
Pulsatilla saponin D
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1 Cited Publications
Cat. No.: HY-N0834
CAS No.: 68027-15-6
Synonyms: SB365; Hederacolchiside A
Category:  

Triterpenes Terpenoids Ranunculaceae Plants Disease Research Fields Pulsatilla chinensis (Bunge) Regel Cancer

Target:  

Apoptosis

Pulsatilla saponin D (SB365), isolated from the root of Pulsatilla chinensis, is an anti-tumor agent .
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1
Hederacolchiside A1
Hederacolchiside A1
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1 Cited Publications
Cat. No.: HY-N6950
CAS No.: 106577-39-3
Category:  

Infection Triterpenes other families Terpenoids Plants Disease Research Fields

Target:  

PI3K Akt mTOR Parasite Apoptosis

Hederacolchiside A1, isolated from Pulsatilla chinensis, suppresses proliferation of tumor cells by inducing apoptosis through modulating PI3K/Akt/mTOR signaling pathway . Hederacolchiside A1 has antischistosomal activity, affecting parasite viability both in vivo and in vitro .
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1
Neoglycyrol
Neoglycyrol
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1 Cited Publications
Cat. No.: HY-N3961
CAS No.: 23013-84-5
Category:  

Cardiovascular Disease Leguminosae Phenols Polyphenols Plants Disease Research Fields Glycyrrhiza uralensis Fisch.

Target:  

Others

Neoglycyrol is isolated from the root of Glycyrrhiza uralensis Fisch . Neoglycyrol is a potential myocardial protection active compound screened from traditional patent medicine Tongmai Yangxin pill (TMYXP) .
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Licoricidin
Licoricidin
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Cat. No.: HY-N3387
CAS No.: 30508-27-1
Category:  

Flavonoids Leguminosae Flavanols Plants Disease Research Fields Glycyrrhiza uralensis Fisch. Inflammation/Immunology

Target:  

Apoptosis NF-κB Akt MMP

Licoricidin (LCD) is isolated from Glycyrrhiza uralensis Fisch, possesses anti-cancer activities. Licoricidin (LCD) inhibit SW480 cells (IC50=7.2 μM) by inducing cycle arrest, apoptosis and autophagy, and is a potential chemopreventive or chemotherapeutic agent against colorectal cancer . Licoricidin (LCD) inhibits Lung Metastasis by inhibition of tumor angiogenesis and lymphangiogenesis as well as changes in the local microenvironment of tumor tissues the anticarcinogenic effect . Licoricidin enhanced gemcitabine-induced cytotoxicity in Osteosarcoma (OS) cells by inactivation of the Akt and NF-κB pathways in vitro and in vivo . Licoricidin blocks UVA-induced photoaging via ROS scavenging, limits the activity of MMP-1, it can be considered as an active ingredient in new topically applied anti-ageing formulations .
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Pulchinenoside A
Pulchinenoside A
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Cat. No.: HY-N0204
CAS No.: 129724-84-1
Synonyms: Anemoside A3
Category:  

Triterpenes Terpenoids Ranunculaceae Other Diseases Plants Disease Research Fields Pulsatilla chinensis (Bunge) Regel

Target:  

NF-κB p38 MAPK

Pulchinenoside A (Anemoside A3) is an orally active triterpenoid glycoside found in the root of Pulsatilla chinensis. Pulchinenoside A has amti-inflammation, antitumor, antidepressant, immunoregulatory and neuroprotective efrects. Pulchinenoside A activates NF-κB/MAPK signaling pathway. Pulchinenoside A can induce relaxing effect in rat renal arteries. Pulchinenoside A can be used for the researches of experimental autoimmune encephalomyelitis, breast cancer, depression and renovascular hypertension .
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23-Hydroxybetulinic acid
23-Hydroxybetulinic acid
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Cat. No.: HY-N0566
CAS No.: 85999-40-2
Synonyms: Anemosapogenin
Category:  

Triterpenes other families Terpenoids Plants Disease Research Fields Cancer

Target:  

Apoptosis Autophagy Bcl-2 Family Caspase Survivin p38 MAPK MMP

23-Hydroxybetulinic acid (Anemosapogenin) is an orally active triterpenoid with broad-spectrum anticancer activity. 23-Hydroxybetulinic acid reduces the levels of Bcl-2 and survivin, elevates the level of Bax, promotes the cleavage/activation of caspase-3 and caspase-9, and induces apoptosis via the endogenous mitochondrial pathway involving cytochrome C release and mitochondrial membrane potential disruption. 23-Hydroxybetulinic acid arrests the cell cycle at S and G1 phases, inhibits cancer cell proliferation, blocks the MAPK signaling pathway, regulates MMP2, and induces autophagic apoptosis by upregulating beclin-1. 23-Hydroxybetulinic acid inhibits the activity and efflux function of P-gp, increases the intracellular accumulation of chemotherapeutic drugs, and synergistically enhances cytotoxicity with Doxorubicin (HY-15142). 23-Hydroxybetulinic acid inhibits the phosphorylation and nuclear translocation of STAT6, blocks M2 macrophage polarization, and reduces M2 macrophage-mediated apoptosis resistance of colon cancer cells. 23-Hydroxybetulinic acid can be used in related studies on chronic myeloid leukemia, hepatocellular carcinoma, sarcoma 180, multidrug-resistant breast cancer, leukemia, Doxorubicin-induced cardiotoxicity, and colorectal cancer .
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HN-saponin F
HN-saponin F
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Cat. No.: HY-N15720
CAS No.: 39524-13-5
Synonyms: Pulsatilla saponin B
Category:  

Triterpenes Caprifoliaceae Terpenoids Plants Lonicera macrantha (D. Don) Spreng. Pentacyclic Triterpenoids

Target:  

Others

HN-saponin F (Pulsatilla saponin B) is an orally active triterpenoid saponin found in Lonicera macranthoides. HN-saponin F exerts anti-inflammatory activity by regulating inflammation-related pathways (e.g., inhibiting pro-inflammatory factor release). HN-saponin F is promising for research of inflammatory diseases .
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Semilicoisoflavone B
Semilicoisoflavone B
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Cat. No.: HY-N1280
CAS No.: 129280-33-7
Category:  

Flavonoids Leguminosae Phenols Polyphenols Plants Glycyrrhiza uralensis Fisch. Isoflavones

Target:  

Amyloid-β

Semilicoisoflavone B, an isoflavone, mainly derived from Glycyrrhiza uralensis Fisch.. Semilicoisoflavone B reduces amyloid β (Aβ) secretion by inhibiting β-secretase-1 (BACE1) expression and activity. Semilicoisoflavone B decreases BACE1 expression mainly through increasing PPARγ expression and inhibiting STAT3 phosphorylation .
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(Rac)-Anemonin
(Rac)-Anemonin
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Cat. No.: HY-N0278A
CAS No.: 90921-11-2
Synonyms: (Rac)-Pulsatilla camphor; (Rac)-Anemonine
Category:  

Natural Products Ranunculaceae Clematis crassifolia Benth. Plants

Target:  

PKC NO Synthase

(Rac)-Anemonin ((Rac)-Pulsatilla camphor) is the diastereoisomer of Anemonin (HY-N0278). Anemonin (Pulsatilla camphor), a selective iNOS inhibitor, is also a PKC-θ inhibitor. Anemonin can significantly inhibit the translation or protein stability of PKC-θ protein. Anemonin also ameliorates dextran sodium sulfate-induced acute ulcerative colitis (UC) in mice. Anemonin can be used in the research of inflammation-related diseases .
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Anemonin
Anemonin
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Cat. No.: HY-N0278
CAS No.: 508-44-1
Synonyms: Pulsatilla camphor; Anemonine; trans-Anemonin
Category:  

Natural Products Ranunculaceae Clematis crassifolia Benth. Plants

Target:  

PKC NO Synthase

Anemonin (Pulsatilla camphor), a selective iNOS inhibitor, is also a PKC-θ inhibitor. Anemonin can significantly inhibit the translation or protein stability of PKC-θ protein. Anemonin also ameliorates dextran sodium sulfate-induced acute ulcerative colitis (UC) in mice. Anemonin can be used in the research of inflammation-related diseases .
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Licoisoflavanone
Licoisoflavanone
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Cat. No.: HY-N7372
CAS No.: 66067-26-3
Category:  

Flavonoids Leguminosae Isoflavanones Other Diseases Phenols Polyphenols Plants Disease Research Fields Glycyrrhiza uralensis Fisch.

Target:  

Apoptosis

Licoisoflavanone is an orally active isoflavane-based immunomodulator with multiple activities including antiviral, anti-inflammatory, cytoprotective and cancer cell apoptosis-inducing effects. Licoisoflavanone can be isolated from the roots and rhizomes of Glycyrrhiza uralensis Fisch. Licoisoflavanone not only enhances the body's immunity, but also effectively prevents acute respiratory distress syndrome and multiple organ damage by alleviating cytokine storm, thereby reducing the degree of inflammation. In rats, Licoisoflavanone undergoes multiple metabolic transformation processes such as glucuronidation, hydroxylation, sulfation, methylation and dehydrogenation. Licoisoflavanone has become an important candidate molecule for research on COVID-19 and related inflammatory diseases .
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Gancaonin M
Gancaonin M
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Cat. No.: HY-N3922
CAS No.: 129145-51-3
Category:  

Flavonoids Leguminosae Plants Glycyrrhiza uralensis Fisch. Isoflavones

Target:  

Others

Gancaonin M is a Flavonoids product that can be isolated from the roots of Glycyrrhiza uralensis Fisch .
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Complanatoside B
Complanatoside B
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Cat. No.: HY-N7903
CAS No.: 142473-99-2
Category:  

Flavonols Flavonoids Monophenols Leguminosae Phenols Plants Astragalus complanatus Bunge var. eutrichus Hand.-Mazz. Disease Research Fields Inflammation/Immunology

Target:  

Others

Complanatoside B is a P. chinense Fisch flavonoid with potential anti-inflammatory effects .
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Rhamnocitrin 3-glucoside
Rhamnocitrin 3-glucoside
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Cat. No.: HY-N11472
CAS No.: 41545-37-3
Synonyms: Rhamnocitrin-3-O-β-D-glucopyranoside
Category:  

Flavonoids Leguminosae Flavones Astragalus membranaceus var. mongholicus (Bunge)P.K.Hsiao Plants

Target:  

Others

Rhamnocitrin 3-glucoside (Rhamnocitrin-3-O-β-D-glucopyranoside) is a natural product that can be isolated from Astragalus membranaceus (Fisch.) Bge. var. mongholicus (Bge.) Hsiao (AM) .
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Uralsaponin C
Uralsaponin C
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Cat. No.: HY-N8609
CAS No.: 1262326-46-4
Category:  

Triterpenes Leguminosae Terpenoids Ketones, Aldehydes, Acids Plants Glycyrrhiza uralensis Fisch.

Target:  

Others

Uralsaponin C is an analogue of oleanane-type triterpenoid saponin. Uralsaponin C can be isolated from the roots of Glycyrrhiza uralensis Fisch .
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Isoliquiritigenin (Standard)
Isoliquiritigenin (Standard)
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Cat. No.: HY-N0102R
CAS No.: 961-29-5
Synonyms: GU17 (Standard); ISL (Standard); Isoliquiritigen (Standard); SJ000286237 (Standard)
Category:  

Flavonoids Microorganisms Chalcones Leguminosae Phenols Polyphenols Plants Glycyrrhiza uralensis Fisch.

Target:  

Reference Standards Aldose Reductase Influenza Virus Autophagy Apoptosis

Isoliquiritigenin (Standard) is the analytical standard of Isoliquiritigenin. This product is intended for research and analytical applications. Isoliquiritigenin is an anti-tumor flavonoid from the root of Glycyrrhiza uralensis Fisch., which inhibits aldose reductase with an IC50 of 320 nM. Isoliquiritigenin is a potent inhibitor of influenza virus replication with an EC50 of 24.7 μM.
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Hederacolchiside A1 (Standard)
Hederacolchiside A1 (Standard)
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Cat. No.: HY-N6950R
CAS No.: 106577-39-3
Category:  

Triterpenes other families Terpenoids Plants

Target:  

Reference Standards PI3K Akt mTOR Parasite Apoptosis

Hederacolchiside A1 (Standard) is the analytical standard of Hederacolchiside A1. This product is intended for research and analytical applications. Hederacolchiside A1, isolated from Pulsatilla chinensis, suppresses proliferation of tumor cells by inducing apoptosis through modulating PI3K/Akt/mTOR signaling pathway . Hederacolchiside A1 has antischistosomal activity, affecting parasite viability both in vivo and in vitro .
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Pulsatilla saponin H
Pulsatilla saponin H
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Cat. No.: HY-N6068
CAS No.: 68027-14-5
Synonyms: Hederacolchiside F
Category:  

Triterpenes Terpenoids Ranunculaceae Other Diseases Plants Disease Research Fields Pulsatilla chinensis (Bunge) Regel

Target:  

Others

Pulsatilla saponin H is a natural compound isolated from the Roots of Pulsatilla koreana .
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